Sean William Scott became a household name for his role as "Steve Stiffler" in the American Pie franchise. His role was a gift just as much a curse: on one hand he became extremely famous for his role as "Stiffler", but on the other, he couldn't get rid of the role itself. In 2011, he admitted himself to a clinic to seek help with personal and health problems.
Stephen Collins' roles as "Eric Camden" in 7th Heaven won him major international success back in the day. Sadly, in October of 2014, a few recordings were released where Collins admits to sexually harassing teenage girls. Ever since the infamous scandal, the offers have drastically disappeared and for good reason.
Freddie Prinze Jr. got his big breakthrough in the movie I Know What You Did Last Summer. By sheer fate, the actor actually met the mother of his future children on the set of the movie. All we see of him nowadays is the occasional guest role on TV.
During the early 90's, Culkin was probably one of the most recognizable child actors of the decade. His role in Home Alone won the then 10-year-old millions upon millions of dollars. Sadly, the fame was too much for Macaulay to handle which led to no further success and a pretty nasty drug problem. He hasn't been cast for anything major since then.
Mel Gibson has been super successful as both an actor and a director throughout his career in Hollywood. Shortly before the premiere of his movie Apocalypto, he was caught driving under the influence which led him to uttering antisemitic slurs on camera. This led to people boycotting his movies and the actor in general. Nowadays he tends to stay behind the camera, but looking at the bright side, he got nominated for an Oscar for directing the movie Hacksaw Ridge back in 2017.
Taylor Lautner found fame in The Twilight Saga, and hasn't seemed to be able to get any other significant roles to keep him in the spotlight.
Meg Ryan had her peak when she starred in movies like When Harry Met Sally..., You've Got Mail and Sleepless in Seattle. Since then, the actress has really lost her place in the spotlight, which is a real shame!
Cameron Diaz absolutely nailed it in the entertainment industry in the early 2000s, but since then some of her starring roles haven't been very successful. It's because of those box office fails that she doesn't seem to be able to stand out in the limelight anymore.
It has been decades since Eddie Murphy has found real success on screen. It is really too bad that this comedic actor can't seem to find any roles or characters to bring him back into the spotlight.
Tobey Maguire was amazing in Sam Raimi's Spider-Man trilogy, but unfortunately for the actor, he hasn't found many leading roles in box office hits since then...