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'Charmed' Stars Alyssa Milano And Holly Marie Combs Will Be Reunited On 'Grey's Anatomy'

Alyssa Milano and Holly Marie Combs will be reunited on season 16 of Grey's Anatomy.

October 11, 2019 - 11:20 / Clemens Fanger

A Charmed reunion is happening this fall - but it will actually take place on Grey's Anatomy! Alyssa Milano and Holly Marie Combs are set to guest star on the popular medical drama and fans are beyond excited!

Holly Marie Combs and Alyssa Milano are returning to TV this fall, but this time they won't be playing "Piper" and "Phoebe Halliwell". The two actresses will appear as guest stars in the upcoming 16th season of Grey's Anatomy where they are reunited with the former Charmed writers Krista Vernoff and Andy Reaser, who are now executive producer's of the popular medical drama.

Alyssa Milano and Holly Marie Combs reunited as sisters on Grey's Anatomy

While the two are not reprising their roles as "Phoebe" and "Piper", they will actually play two sisters who come to Grey Sloan Memorial to check on their other sister who's been admitted after an accident.

ABC shared a snap shot from the episode on the show's Instagram account and captioned it "We're excited to have the charmed ones @milano_alyssa and @thehmc guest-starring on #GreysAnatomy! #CastFromThePast".

The network as well as the main cast aren't the only ones excited about this Charmed reunion, as Twitter quickly erupted with praises from fans for this amazing guest appearance. Stay tuned for more as Grey's Anatomy returns to ABC with season 16 on September 26.