Nobody was very fond of "Jen Lindley" (Michelle Williams) when she moved to Capeside on Dawson's Creek. Although over time, fans began to love "Lindley" more and more as the show progressed, which made her death all the more tragic. Our beloved "Jen" died in the series finale of the show from a heart disease - the silver lining being that she left her legacy, in form of a baby, behind.
It was by far one of the most tragic deaths in TV history. At the end of the 11th season of the show, "Dr. Derek Shepherd" (Patrick Dempsey) got into a vicious car accident and sadly passed away. "Shepherd" left behind his wife "Meredith Grey" (Ellen Pompeo) and his kids. Fans were so shocked that they even started a petition to get Dempsey's character back on the air.
Dominic Monaghan's character, "Charlie Pace", died a real hero's death on the hit series LOST. Our hero died during a risky attempt to enable radio communication for the rest of the people on the island. Before "Pace" drowned, he was able to deliver an important message to his friends which in return brought them to safety.
Even "Edie Britt's" death on the show Desperate Housewives was a huge shock for fans in general. The real estate agent became popular for her sassy remarks. Nobody could do the dirty laundry like she did! While she was fleeing desperately from her mentally troubled husband, "Dave Williams" (Neal McDonough), her neighbor "Orson Hodge" (Kyle MacLachlan) suddenly appeared on the street. "Britt'" lost control of her car and crashed into a pole. While coming out of the car, she was hit by an electric shock which ultimately killed her. She died surrounded by her friends.
Fans everywhere burst into tears after watching this character pass away. "Denny Duquette" (Jeffrey Dean Morgan), from the hit series Grey's Anatomy, died after a heart transplant at Seattle Grace Hospital. The love of his life, "Dr. Isobel Stevens" (Katherine Heigl) was always by his side and he even proposed to her just before he died. He never got an answer.
Mischa Barton played the role of "Marissa Cooper" for three seasons on the show The O.C.. She had survived numerous escapades with drugs and alcohol before, so her death came quite unexpected. She died in her boyfriend "Ryan's (Benjamin McKenzie) arms, after their car overturned several times."Ryan" was able to save "Marissa" before their car exploded. Nevertheless, she died shortly after.
The loss of "Angel" (David Boreanaz) on Buffy The Vampire Slayer was difficult for fans to cope with. Shortly before his demise, he confessed his love to "Buffy" (Sarah Michelle Gellar). With a heavy heart, he had to ram a sword in his chest to eliminate the evil. "Angel" was missed so much by his fans, that he got his own spin-off series.
Two and a Half Men just never was the same without "Charlie Harper" (Charlie Sheen). "Charlie" was run over by an ocoming subway in catacombs of Paris. His stalker, "Rose" (Melanie Lynskey) was a possible suspect when she returned to the show as a widow. Fans were given some form of hope when they found out that "Rose" had been keeping "Charlie" hostage in her basement the entire time. In the series finale, we see "Charlie" standing outside his house again - unfortunately, he is then killed by a falling piano...
Anthony Edwards played "Mark Greene" for the better part of 8 seasons in the hit series E.R". After suffering from cancer for an extended period of time, "Mark" eventually succumbed to the disease. Sadly, he had thought that he had eventually won his fight against cancer. "Greene" died in his wife and daughter's arms with his last sight directed towards the ocean. A sad day for all E.R. fans.
When "Ally McBeal's" (Calista Flockhart) childhood sweetheart "Billy Thomas" (Gil Bellows) unexpectedly died, fans of the show were completely devasted. "Thomas" died from a brain tumor and his passsing emotionally destroyed "Ally". During his funeral, she gave a an emotional speech, even though the last words he said were that he loved "Georgia".
The death of T.R. Knight's character "George O'Malley" on Grey's Anatomy was solved towards the end of the series. This was one of the most dramatic deaths in TV history. Fans didn't know that their favorite character was on "Meredith Grey's" operating table. "George" was run over by a bus and couldn't be identified until wrote his nickname into the palm of "Meredith's" hand. Her screams can still be heard today.